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China Biggest factory manufacturer offer Vitamin A Palmitate CAS 79-81-2

Model No.︰79-81-2
Brand Name︰Leader
Country of Origin︰China
Unit Price︰US $ 1 / KG
Minimum Order︰500 KG
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Product Description
Vitamin A palmitate Basic information
Product Name: Vitamin A palmitate
Synonyms: VitaminAPalmitateinOil;VITAMINAPALMITATE,LIQUIDINOIL,1MILLIONIU/G;VITAMINAPALMITATE,USP;[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenyl] hexadecanoate;VITAMIN A PALMITATE(RETINYL PALMITATE)(P);VITAMIN A PALMITATE(RETINYL PALMITATE)(RG);ALL-TRANS-RETINYLPALMITATE;Retinylpalmitat
CAS: 79-81-2
MF: C36H60O2
MW: 524.86
EINECS: 201-228-5
Product Categories: BAYPRESS;Vitamins and derivatives
Mol File: 79-81-2.mol
Vitamin A palmitate Structure
 
Vitamin A palmitate Chemical Properties
Melting point  28-29℃
Boiling point  546.51°C (rough estimate)
density  0.9668 (rough estimate)
refractive index  1.5250 (estimate)
Fp  194℃
storage temp.  2-8°C
form  oil
Specific Gravity 0.90~0.93 (20℃)
Water Solubility  Soluble in chloroform, ether, and vegetable oils. Insoluble in water.
Merck  13,10073
BRN  1917366
InChIKey VYGQUTWHTHXGQB-YFAKFODJSA-N
CAS DataBase Reference 79-81-2(CAS DataBase Reference)
NIST Chemistry Reference Vitamin a palmitate(79-81-2)
EPA Substance Registry System Retinol, hexadecanoate (79-81-2)
 
Safety Information
Hazard Codes  T,Xn,F
Risk Statements  63-53-61-11
Safety Statements  53-23-36/37/39-45-36/37-16-60
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  3
RTECS  VH6860000
8-10-23
TSCA  Yes
HS Code  29362100
Toxicity LD50 (10 day) in mice, rats (mg/kg): 6060, 7910 orally (Kamm)
 
MSDS Information
Provider Language
SigmaAldrich English
 
Vitamin A palmitate Usage And Synthesis
Chemical Properties 95.0-100.5% Absorbance @325 nm ≥0.85%
Uses antihypertensive
Uses all-trans-Retinyl Palmitate is an ester derivative of Retinol (R252000). all-trans-Retinyl Palmitate is used as a vitamin supplement in the treatment of Vitamin A deficiency. all-trans-Retinyl Palmita te is used as an antioxidant and a source of vitamin A added to low fat milk and other dairy products. all-trans-Retinyl Palmitate is also a constituent of some topically applied skin care products
Uses retinyl palmitate is a skin conditioner. This retinoid is considered a milder version of retinoic acid, given its conversion properties. once on the skin, it converts to retinol, which in turn converts to retinoic acid. Physiologically, it is credited with increasing R epidermal thickness, stimulating the production of more epidermal protein, and increasing skin elasticity. Cosmetically, retinyl palmitate is used to reduce the number and depth of fine lines and wrinkles, and prevent skin roughness resulting from uV exposure. Secondary reactions such as erythema, dryness, or irritation are not associated with retinyl palmitate. It is even more effective when used in combination with glycolic acid because it achieves greater penetration. In the united States, its maximum usage level in cosmetic formulations is 2 percent. Retinyl palmitate is the ester of retinol and palmitic acid.
Uses vitamin A palmitate is known as a skin “normalizer.” It acts as an antikeratinizing agent, helping the skin stay soft and plump, and improving its water-barrier properties. Because of its impact on the skin’s water-barrier properties, it is useful against dryness, heat, and pollution. It is also an anti-oxidant and is suggested for use in sunscreens. Clinical studies with vitamin A palmitate indicate a significant change in skin composition, with increases in collagen, DnA, skin thickness, and elasticity. Vitamin A palmitate’s stability is superior to retinol.
Safety Profile Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods The palmitate is separated from retinol by column chromatography on water-deactivated alumina with hexane containing a very small percentage of acetone. It is also chromatographed on TLC silica gel G, using pet ether/isopropyl ether/acetic acid/water (180:20:2:5) or pet ether/acetonitrile/acetic acid/water (190:10:1:15) to develop the chromatogram. It is then recrystallised from propylene at low temperature (below -47o). [Beilstein 6 IV 4135.]
 
Vitamin A palmitate Preparation Products And Raw materials
Payment Terms︰TT
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